The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

The RgpA-Kgp proteinase-adhesin complexes are a primary virulence factor of Porphyromonas gingivalis, a major pathogen in the development of chronic periodontitis. The RgpA-Kgp complexes have been suggested to bias the immune response to a Th2 phenotype in disease by hydrolysis of Th1 cytokines. Her...

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Detalles Bibliográficos
Main Authors: Tam, Vivian, O'Brien-Simpson, Neil M., Chen, Yu-Yen, Sanderson, Colin J., Kinnear, Beverley, Reynolds, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663161/
https://ncbi.nlm.nih.gov/pubmed/19168731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01377-08
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