Steady-State Pharmacokinetics of Abacavir in Plasma and Intracellular Carbovir Triphosphate following Administration of Abacavir at 600 Milligrams Once Daily and 300 Milligrams Twice Daily in Human Immunodeficiency Virus-Infected Subjects

Abacavir (ABC) is administered either at 600 mg once daily (ABC 600 mg QD) or 300 mg twice daily (ABC 300 mg BID) in anti-human immunodeficiency virus (anti-HIV) combination therapy. Although ABC plasma pharmacokinetics following each regimen has been well defined, no study has directly compared the...

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Detalhes bibliográficos
Main Authors: Moyle, Graeme, Boffito, Marta, Fletcher, Carl, Higgs, Chris, Hay, Phillip E., Song, Ivy H., Lou, Yu, Yuen, Geoffrey J., Min, Sherene S., Guerini, Elena M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663118/
https://ncbi.nlm.nih.gov/pubmed/19188387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01000-08
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