Antistaphylococcal Activity of Dihydrophthalazine Antifolates, a Family of Novel Antibacterial Drugs

For a panel of 153 Staphylococcus aureus clinical isolates (including 13 vancomycin-intermediate or heterogeneous vancomycin-intermediate and 4 vancomycin-resistant strains), MIC(50)s and MIC(90)s of three novel dihydrophthalazine antifolates, BAL0030543, BAL0030544, and BAL0030545, were 0.03 and 0....

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Autores principales: Clark, Catherine, Ednie, Lois M., Lin, Gengrong, Smith, Kathy, Kosowska-Shick, Klaudia, McGhee, Pamela, Dewasse, Bonifacio, Beachel, Linda, Caspers, Patrick, Gaucher, Bérangère, Mert, Gürkan, Shapiro, Stuart, Appelbaum, Peter C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Susceptibility
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663101/
https://ncbi.nlm.nih.gov/pubmed/19188385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01619-08
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