Gadolinium conjugated TiO(2)-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T(1)-weighted contrast enhancement in Magnetic Resonance images

Nanoconjugates composed of TiO(2) nanoparticles, DNA oligonucleotides and a gadolinium contrast agent were synthesized for use in magnetic resonance imaging. Transfection of cultured cancer cells with these nanoconjugates showed them to be superior to the free contrast agent of same formulation with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Paunesku, Tatjana, Ke, Tianyi, Dharmakumar, Rohan, Mascheri, Nicole, Wu, Aiguo, Lai, Barry, Vogt, Stefan, Maser, Jörg, Thurn, Kenneth, Szolc-Kowalska, Barbara, Larson, Andrew, Bergan, Raymond C, Omary, Reed, Li, Debiao, Lu, Zheng-Rong, Woloschak, Gayle E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663023/
https://ncbi.nlm.nih.gov/pubmed/18567541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.04.004
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