Gadolinium conjugated TiO(2)-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T(1)-weighted contrast enhancement in Magnetic Resonance images

Nanoconjugates composed of TiO(2) nanoparticles, DNA oligonucleotides and a gadolinium contrast agent were synthesized for use in magnetic resonance imaging. Transfection of cultured cancer cells with these nanoconjugates showed them to be superior to the free contrast agent of same formulation with...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Paunesku, Tatjana, Ke, Tianyi, Dharmakumar, Rohan, Mascheri, Nicole, Wu, Aiguo, Lai, Barry, Vogt, Stefan, Maser, Jörg, Thurn, Kenneth, Szolc-Kowalska, Barbara, Larson, Andrew, Bergan, Raymond C, Omary, Reed, Li, Debiao, Lu, Zheng-Rong, Woloschak, Gayle E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2008
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663023/
https://ncbi.nlm.nih.gov/pubmed/18567541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.04.004
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