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Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1

OBJECTIVE: Endometrial cancer is the most common type of gynecologic cancer in the United States. In this study, we propose that a marine sponge compound, psammaplysene A (PsA) induces apoptosis in endometrial cancer cells through forced nuclear expression of FOXO1. METHODS: Ishikawa and ECC1 cells...

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Autors principals: Berry, Emily, Hardt, Jennifer L., Clardy, Jon, Lurain, John R., Kim, J. Julie
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662924/
https://ncbi.nlm.nih.gov/pubmed/19041124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2008.10.017
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