Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis

Leptin, a hormone mainly produced from adipose tissue, has been shown to induce proliferation of cancer cells. However, the molecular mechanisms underlying leptin-induced tumor progression have not been clearly elucidated. In the present study, we investigated the role of autophagy in leptin-induced...

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Vydáno v:Oncotarget
Hlavní autoři: Nepal, Saroj, Kim, Mi Jin, Hong, Jin Tae, Kim, Sang Hyun, Sohn, Dong-Hwan, Lee, Sung Hee, Song, Kyung, Choi, Dong Young, Lee, Eung Seok, Park, Pil-Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466676/
https://ncbi.nlm.nih.gov/pubmed/25704884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.3347
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