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Sequential Tyrosine Sulfation of CXCR4 by Tyrosylprotein Sulfotransferases

The CXC-chemokine receptor 4 (CXCR4) is a G protein-coupled receptor for stromal cell-derived factor-1 (SDF-1/CXCL12). SDF-1 induced CXCR4 signaling is indispensable for embryonic development and crucial for immune cell homing and has been implicated in metastasis of numerous types of cancer. CXCR4...

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Detalhes bibliográficos
Main Authors: Seibert, Christoph, Veldkamp, Christopher T., Peterson, Francis C., Chait, Brian T., Volkman, Brian F., Sakmar, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662774/
https://ncbi.nlm.nih.gov/pubmed/18834145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800965m
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