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Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR

Activation of dendritic cells (DCs) leads to cell maturation, which is accompanied by a regulated pattern of gene expression changes. Two significant and contradictory consequences of DC activation are that, although activation is necessary for maximal T-cell stimulation, it also leads to the initia...

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Hlavní autoři: Wang, Tianhong, Jiang, Qiong, Chan, Camie, Gorski, Kevin S., McCadden, Erin, Kardian, David, Pardoll, Drew, Whartenby, Katharine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662637/
https://ncbi.nlm.nih.gov/pubmed/19164597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-176354
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