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Plasma membrane Ca(2+)-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents
How Ca(2+)-dependent signaling effectors are regulated in cardiomyocytes, given the extreme cytoplasmic Ca(2+) concentration changes that underlie contraction, remains unknown. Cardiomyocyte plasma membrane Ca(2+)-ATPase (PMCA) extrudes Ca(2+) but has little effect on excitation-contraction coupling...
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Autori principali: | , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Clinical Investigation
2009
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662553/ https://ncbi.nlm.nih.gov/pubmed/19287093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36693 |
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