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Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid

Treatments for primary and metastatic melanomas are rarely effective. Even therapeutics such as retinoic acid (RA) that are successfully used to treat several other forms of cancer are ineffective. Recent evidence indicates that the antiproliferative effects of RA are mediated by the transcription f...

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Autors principals: Passeron, Thierry, Valencia, Julio C., Namiki, Takeshi, Vieira, Wilfred D., Passeron, Hélène, Miyamura, Yoshinori, Hearing, Vincent J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662541/
https://ncbi.nlm.nih.gov/pubmed/19273910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34015
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