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Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53
The question of whether or not stem cell loss drives aging in the brain is not fully resolved. Here, we used mice over-expressing the short isoform of p53 (ΔNp53 or p44) as a model of aging to gain insight into the cellular mechanisms underlying age-related brain functional deficits. By BrdU labelin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662499/ https://ncbi.nlm.nih.gov/pubmed/17850928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.07.016 |
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