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Running on empty: how p53 controls INS/IGF signaling and affects lifespan
In higher organisms dependent on the regenerative ability of tissue stem cells to maintain tissue integrity throughout adulthood, the failure of stem cells to replace worn out, dead, or damaged cells is seen as one mechanism that limits lifespan. In these organisms, tumor suppressors such as p53 are...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764313/ https://ncbi.nlm.nih.gov/pubmed/18598747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2008.05.017 |
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