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A potentially deleterious new CYP2C9 polymorphism identified in an African American patient with major hemorrhage on warfarin therapy

Possession of a variant Cytochrome P450 2C9 (CYP2C9) genotype has been associated with a higher risk of hemorrhagic complications among warfarin users. [1; 2] Although the influence of the common variant alleles (CYP2C9*2, CYP2C9*3) on warfarin response is well documented that of other rare defectiv...

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Hlavní autoři: JA, Goldstein, JA, Blaisdell, Limdi, NA
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662477/
https://ncbi.nlm.nih.gov/pubmed/19083245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2008.10.011
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