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Activation of the Aryl Hydrocarbon Receptor by TCDD Inhibits Senescence: A Tumor Promoting Event?

Activation of the aryl hydrocarbon receptor (AHR) by the agonist, 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) has been shown to promote tumor formation in both liver and skin. In the liver, but not the skin, the AHR-mediated events that contribute to TCDD’s tumor promoting activities have been studie...

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Detalhes bibliográficos
Main Authors: Ray, S., Swanson, H.I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662439/
https://ncbi.nlm.nih.gov/pubmed/19100242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.11.022
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