In situ imaging reveals different responses by naïve and memory CD8 T cells to late antigen presentation by lymph node DC after influenza virus infection

Pulmonary influenza infection causes prolonged lymph node hypertrophy while processed viral antigens continue to be presented to virus-specific CD8 T cells. We show that naïve, but not central/memory, nucleoprotein (NP)-specific CD8 T cells recognized antigen-bearing CD11b(+) DC in the DLN more than...

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Hauptverfasser: Khanna, Kamal M., Aguila, Carolina C., Redman, Jason M., Suarez-Ramirez, Jenny E., Lefrançois, Leo, Cauley, Linda S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662394/
https://ncbi.nlm.nih.gov/pubmed/19009527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838602
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