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PP2A dephosphorylates Elf-1 and determines the expression of CD3ζ and FcRγ in human systemic lupus erythematosus T cells
T cells from patients with systemic lupus erythematosus are characterized by decreased expression of CD3ζ chain and increased expression of FcRγ chain which becomes part of the CD3 complex and contributes to aberrant signaling. Elf-1 enhances the expression of CD3ζ, whereas it suppresses the express...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662392/ https://ncbi.nlm.nih.gov/pubmed/18714041 |
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