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Crystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination Suppression

DNA recombination events need to be strictly regulated, because an increase in the recombinational frequency causes unfavorable alteration of genetic information. Recent studies revealed the existence of a novel anti-recombination enzyme, MutS2. However, the mechanism by which MutS2 inhibits homolog...

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Detalhes bibliográficos
Main Authors: Fukui, Kenji, Nakagawa, Noriko, Kitamura, Yoshiaki, Nishida, Yuya, Masui, Ryoji, Kuramitsu, Seiki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662267/
https://ncbi.nlm.nih.gov/pubmed/18838375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806755200
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