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Crystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination Suppression

DNA recombination events need to be strictly regulated, because an increase in the recombinational frequency causes unfavorable alteration of genetic information. Recent studies revealed the existence of a novel anti-recombination enzyme, MutS2. However, the mechanism by which MutS2 inhibits homolog...

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Bibliografski detalji
Glavni autori: Fukui, Kenji, Nakagawa, Noriko, Kitamura, Yoshiaki, Nishida, Yuya, Masui, Ryoji, Kuramitsu, Seiki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662267/
https://ncbi.nlm.nih.gov/pubmed/18838375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806755200
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