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Crystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination Suppression
DNA recombination events need to be strictly regulated, because an increase in the recombinational frequency causes unfavorable alteration of genetic information. Recent studies revealed the existence of a novel anti-recombination enzyme, MutS2. However, the mechanism by which MutS2 inhibits homolog...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662267/ https://ncbi.nlm.nih.gov/pubmed/18838375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806755200 |
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