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On the Mechanism of Pore Formation by Melittin

The mechanism of pore formation of lytic peptides, such as melittin from bee venom, is thought to involve binding to the membrane surface, followed by insertion at threshold levels of bound peptide. We show that in membranes composed of zwitterionic lipids, i.e. phosphatidylcholine, melittin not onl...

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Autori principali: van den Bogaart, Geert, Guzmán, Jeanette Velásquez, Mika, Jacek T., Poolman, Bert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662212/
https://ncbi.nlm.nih.gov/pubmed/18819911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805171200
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