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Mcm Subunits Can Assemble into Two Different Active Unwinding Complexes
The replication fork helicase in eukaryotes is a large complex that is composed of Mcm2-7, Cdc45, and GINS. The Mcm2-7 proteins form a heterohexameric ring that hydrolyzes ATP and provide the motor function for this unwinding complex. A comprehensive study of how individual Mcm subunit biochemical a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662182/ https://ncbi.nlm.nih.gov/pubmed/18801730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804686200 |
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