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A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms

Cardiac hypertrophy is an initial physiological adaptive response by the heart to pressure overload. However, if pressure overload persists, frequently, the heart decompensates and develops ‘pathophysiological’ hypertrophy. This leads to increased mortality and morbidity and is an independent risk f...

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Detalhes bibliográficos
Main Authors: Nakagami, Hironori, Jensen, Kristin S, Liao, James K
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662041/
https://ncbi.nlm.nih.gov/pubmed/14572163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07853890310001294
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