Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

Exosomes are secreted cellular vesicles that can be internalized by dendritic cells (DCs), contributing to antigen-specific naive CD4(+) T-cell activation. Here, we demonstrate that human immunodeficiency virus type 1 (HIV-1) can exploit this exosome antigen-dissemination pathway intrinsic to mature...

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Detalhes bibliográficos
Main Authors: Izquierdo-Useros, Nuria, Naranjo-Gómez, Mar, Archer, Jacob, Hatch, Steven C., Erkizia, Itziar, Blanco, Julià, Borràs, Francesc E., Puertas, Maria Carmen, Connor, John H., Fernández-Figueras, Maria Teresa, Moore, Landon, Clotet, Bonaventura, Gummuluru, Suryaram, Martinez-Picado, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661860/
https://ncbi.nlm.nih.gov/pubmed/18945959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158642
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