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The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein

BACKGROUND: Since cell-mediated infection of human immunodeficiency virus type 1 (HIV-1) is more efficient than cell-free infection, cell-to-cell propagation plays a crucial role in the pathogenesis of HIV-1 infection. Transmission of HIV-1 is enabled by two types of cellular contacts, namely, virol...

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Detalhes bibliográficos
Main Authors: Rodriguez-Plata, Maria T, Puigdomènech, Isabel, Izquierdo-Useros, Nuria, Puertas, Maria C, Carrillo, Jorge, Erkizia, Itziar, Clotet, Bonaventura, Blanco, Julià, Martinez-Picado, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640963/
https://ncbi.nlm.nih.gov/pubmed/23590845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-42
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