The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer

Vascular endothelial growth factor (VEGF)-A inhibitors exhibit unseen high responses and toxicity in recurrent epithelial ovarian cancer suggesting an important role for the VEGF/VEGFR pathway. We studied the correlation of VEGF signalling and AKT/mTOR signalling. Using a tissue microarray of clinic...

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Detalhes bibliográficos
Main Authors: Trinh, X B, Tjalma, W A A, Vermeulen, P B, Van den Eynden, G, Van der Auwera, I, Van Laere, S J, Helleman, J, Berns, E M J J, Dirix, L Y, van Dam, P A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661789/
https://ncbi.nlm.nih.gov/pubmed/19240722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604921
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