Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D(1) in Enhancing Human β-Cell Replication and Function In Vivo

OBJECTIVES: To comprehensively inventory the proteins that control the G1/S cell cycle checkpoint in the human islet and compare them with those in the murine islet, to determine whether these might therapeutically enhance human β-cell replication, to determine whether human β-cell replication can b...

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Detalhes bibliográficos
Main Authors: Fiaschi-Taesch, Nathalie, Bigatel, Todd A., Sicari, Brian, Takane, Karen K., Salim, Fatima, Velazquez-Garcia, Silvia, Harb, George, Selk, Karen, Cozar-Castellano, Irene, Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661601/
https://ncbi.nlm.nih.gov/pubmed/19136653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0631
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