An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association

Numerous quantitative trait loci (QTLs) affecting bone traits have been identified in the mouse; however, few of the underlying genes have been discovered. To improve the process of transitioning from QTL to gene, we describe an integrative genetics approach, which combines linkage analysis, express...

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Detalhes bibliográficos
Main Authors: Farber, Charles R, van Nas, Atila, Ghazalpour, Anatole, Aten, Jason E, Doss, Sudheer, Sos, Brandon, Schadt, Eric E, Ingram-Drake, Leslie, Davis, Richard C, Horvath, Steve, Smith, Desmond J, Drake, Thomas A, Lusis, Aldons J
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661539/
https://ncbi.nlm.nih.gov/pubmed/18767929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080908
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