Alternative Splicing of the Guanylyl Cyclase-A Receptor Modulates Atrial Natriuretic Peptide Signaling

Atrial (ANP) and B-type natriuretic peptides (BNP) modulate blood pressure and volume through the stimulation of cyclic GMP production by their guanylyl cyclase-A (GC-A) receptor. A novel isoform of GC-A has been identified that is the result of differential splicing of exon 4. The deletion of a 51-...

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Bibliographic Details
Main Authors: Hartmann, Michael, Skryabin, Boris V., Müller, Thomas, Gazinski, Alexandra, Schröter, Juliane, Gassner, Birgit, Nikolaev, Viacheslav O., Bünemann, Moritz, Kuhn, Michaela
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661397/
https://ncbi.nlm.nih.gov/pubmed/18713751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805521200
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