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PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool

Nuclear domains of promyelocytic leukemia protein (PML) are known to act as signaling nodes in many cellular processes. Although the impact of PML expression in driving cell fate decisions for injured cells is well established, the function of PML in the context of tissue development is less well un...

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Главные авторы: Li, Wenjing, Ferguson, Brian J., Khaled, Walid T., Tevendale, Maxine, Stingl, John, Poli, Valeria, Rich, Tina, Salomoni, Paolo, Watson, Christine J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660741/
https://ncbi.nlm.nih.gov/pubmed/19261859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807640106
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