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Immunotherapeutic Mechanisms of Anti-CD20 Monoclonal Antibodies

The anti-CD20, B cell-specific mAb rituximab (RTX) has been approved for treatment of non-Hodgkin's B cell lymphoma and rheumatoid arthritis. Under conditions of high B cell burden, exhaustion of the body's effector mechanisms, e.g. NK cell-mediated killing, may lead to substantial decreas...

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Hlavní autoři: Taylor, Ronald P., Lindorfer, Margaret A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660201/
https://ncbi.nlm.nih.gov/pubmed/18585457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.05.011
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