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Macrophages are not the source of injurious interleukin-18 in ischemic acute kidney injury in mice
We previously reported in ischemic acute kidney injury (AKI) in mice that caspase-1-mediated production of interleukin-18 (IL-18) is pathogenic and that macrophage depletion by liposome-encapsulated clodronate (LEC) is protective. Therefore, our aim was to determine whether macrophages are a source...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660194/ https://ncbi.nlm.nih.gov/pubmed/19129255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90634.2008 |
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