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Macrophages are not the source of injurious interleukin-18 in ischemic acute kidney injury in mice

We previously reported in ischemic acute kidney injury (AKI) in mice that caspase-1-mediated production of interleukin-18 (IL-18) is pathogenic and that macrophage depletion by liposome-encapsulated clodronate (LEC) is protective. Therefore, our aim was to determine whether macrophages are a source...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: He, Zhibin, Dursun, Belda, Oh, Dong-Jin, Lu, Lawrence, Faubel, Sarah, Edelstein, Charles L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660194/
https://ncbi.nlm.nih.gov/pubmed/19129255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90634.2008
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