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Deletion of SM-B, the high ATPase isoform of myosin, upregulates the PKC-mediated signal transduction pathway in murine urinary bladder smooth muscle

Detrusor smooth muscle (DSM) hypertrophy induced by partial bladder outlet obstruction (PBOO) is associated with changes in the NH(2)-terminal myosin heavy chain isoform from predominantly SM-B to SM-A, alteration in the Ca(2+) sensitization pathway, and the contractile characteristics from phasic t...

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Autores principales: Hypolite, Joseph A., Chang, Shaohua, LaBelle, Edward, Babu, Gopal J., Periasamy, Muthu, Wein, Alan J., Chacko, Samuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660183/
https://ncbi.nlm.nih.gov/pubmed/19052105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90221.2008
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