Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver

Thyrotoxicosis increases endogenous glucose production (EGP) and induces hepatic insulin resistance. We have recently shown that these alterations can be modulated by selective hepatic sympathetic and parasympathetic denervation, pointing to neurally mediated effects of thyroid hormone on glucose me...

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Autori principali: Klieverik, Lars P., Janssen, Sarah F., van Riel, Annelieke, Foppen, Ewout, Bisschop, Peter H., Serlie, Mireille J., Boelen, Anita, Ackermans, Mariëtte T., Sauerwein, Hans P., Fliers, Eric, Kalsbeek, Andries
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660059/
https://ncbi.nlm.nih.gov/pubmed/19321430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805355106
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