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Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver

Thyrotoxicosis increases endogenous glucose production (EGP) and induces hepatic insulin resistance. We have recently shown that these alterations can be modulated by selective hepatic sympathetic and parasympathetic denervation, pointing to neurally mediated effects of thyroid hormone on glucose me...

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Bibliographische Detailangaben
Hauptverfasser: Klieverik, Lars P., Janssen, Sarah F., van Riel, Annelieke, Foppen, Ewout, Bisschop, Peter H., Serlie, Mireille J., Boelen, Anita, Ackermans, Mariëtte T., Sauerwein, Hans P., Fliers, Eric, Kalsbeek, Andries
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660059/
https://ncbi.nlm.nih.gov/pubmed/19321430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805355106
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