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Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver

Thyrotoxicosis increases endogenous glucose production (EGP) and induces hepatic insulin resistance. We have recently shown that these alterations can be modulated by selective hepatic sympathetic and parasympathetic denervation, pointing to neurally mediated effects of thyroid hormone on glucose me...

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Detalhes bibliográficos
Main Authors: Klieverik, Lars P., Janssen, Sarah F., van Riel, Annelieke, Foppen, Ewout, Bisschop, Peter H., Serlie, Mireille J., Boelen, Anita, Ackermans, Mariëtte T., Sauerwein, Hans P., Fliers, Eric, Kalsbeek, Andries
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660059/
https://ncbi.nlm.nih.gov/pubmed/19321430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805355106
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