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Interaction between CXCR4 and CCL20 Pathways Regulates Tumor Growth

The chemokine receptor CXCR4 and its ligand CXCL12 is overexpressed in the majority of tumors and is critically involved in the development and metastasis of these tumors. CXCR4 is expressed in malignant tumor cells whereas its ligand SDF-1 (CXCL12) is expressed mainly by cancer associated fibroblas...

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Detalhes bibliográficos
Main Authors: Beider, Katia, Abraham, Michal, Begin, Michal, Wald, Hanna, Weiss, Ido D., Wald, Ori, Pikarsky, Eli, Abramovitch, Rinat, Zeira, Evelyne, Galun, Eithan, Nagler, Arnon, Peled, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659745/
https://ncbi.nlm.nih.gov/pubmed/19340288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005125
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