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Gene expression and internalization following vector adsorption to immobilized proteins: dependence on protein identity and density

BACKGROUND: Gene delivery by non-specific adsorption of non-viral vectors to protein-coated surfaces can reduce the amount of DNA required, and also increase transgene expression and the number of cells expressing the transgene. The protein on the surface mediates cell adhesion and vector immobiliza...

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Autors principals: Bengali, Zain, Rea, Jennifer C., Shea, Lonnie D.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659664/
https://ncbi.nlm.nih.gov/pubmed/17533618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1058
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