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Peptide-Mediated Lipofection Is Governed by Lipoplex Physical Properties and the Density of Surface-Displayed Amines

Peptides can potentiate lipid-mediated gene delivery by modifying lipoplex physiochemical properties to overcome rate-limiting steps to gene transfer. The objectives of this study were to determine the regimes over which cationic peptides enhance lipofection and to investigate the mechanism of actio...

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Detalhes bibliográficos
Main Authors: REA, JENNIFER C., BARRON, ANNELISE E., SHEA, LONNIE D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648398/
https://ncbi.nlm.nih.gov/pubmed/18306277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21338
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