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Peptide-Mediated Lipofection Is Governed by Lipoplex Physical Properties and the Density of Surface-Displayed Amines
Peptides can potentiate lipid-mediated gene delivery by modifying lipoplex physiochemical properties to overcome rate-limiting steps to gene transfer. The objectives of this study were to determine the regimes over which cationic peptides enhance lipofection and to investigate the mechanism of actio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648398/ https://ncbi.nlm.nih.gov/pubmed/18306277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21338 |
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