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Enhancing Akt imaging through targeted reporter expression
The serine/threonine kinase PKB/Akt is a key mediator of survival and resistance to cancer therapy. Pharmacological inhibition of Akt and its biologic sequelae may significantly impact the treatment of cancer. The use of molecular imaging technologies has contributed significantly to drug discovery...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659640/ https://ncbi.nlm.nih.gov/pubmed/19123987 |
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