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Enhancing Akt imaging through targeted reporter expression

The serine/threonine kinase PKB/Akt is a key mediator of survival and resistance to cancer therapy. Pharmacological inhibition of Akt and its biologic sequelae may significantly impact the treatment of cancer. The use of molecular imaging technologies has contributed significantly to drug discovery...

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Detalhes bibliográficos
Main Authors: Zhang, Limin, Bhojani, Mahaveer S, Ross, Brian D, Rehemtulla, Alnawaz
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659640/
https://ncbi.nlm.nih.gov/pubmed/19123987
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