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Enhancing Akt imaging through targeted reporter expression

The serine/threonine kinase PKB/Akt is a key mediator of survival and resistance to cancer therapy. Pharmacological inhibition of Akt and its biologic sequelae may significantly impact the treatment of cancer. The use of molecular imaging technologies has contributed significantly to drug discovery...

詳細記述

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書誌詳細
主要な著者: Zhang, Limin, Bhojani, Mahaveer S, Ross, Brian D, Rehemtulla, Alnawaz
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659640/
https://ncbi.nlm.nih.gov/pubmed/19123987
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