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PHARMACOLOGICAL ENHANCEMENT OF ENDOCANNABINOID SIGNALING REDUCES THE CHOLINERGIC TOXICITY OF DIISOPROPYLFLUOROPHOSPHATE

Diisopropylfluorophosphate (DFP) elicits cholinergic toxicity by inhibiting acetylcholinesterase, leading to accumulation of the neurotransmitter acetylcholine and excessive stimulation of cholinergic receptors throughout the body. Endocannabinoids inhibit the release of neurotransmitters including...

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Detalhes bibliográficos
Main Authors: Nallapaneni, Anuradha, Liu, Jing, Karanth, Subramanya, Pope, Carey
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659532/
https://ncbi.nlm.nih.gov/pubmed/18765251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2008.08.001
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