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PHARMACOLOGICAL ENHANCEMENT OF ENDOCANNABINOID SIGNALING REDUCES THE CHOLINERGIC TOXICITY OF DIISOPROPYLFLUOROPHOSPHATE
Diisopropylfluorophosphate (DFP) elicits cholinergic toxicity by inhibiting acetylcholinesterase, leading to accumulation of the neurotransmitter acetylcholine and excessive stimulation of cholinergic receptors throughout the body. Endocannabinoids inhibit the release of neurotransmitters including...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659532/ https://ncbi.nlm.nih.gov/pubmed/18765251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2008.08.001 |
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