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Synthesis and Biological Evaluation of a 5-6-5 Imidazole-Phenyl-Thiazole Based α-Helix Mimetic
[Image: see text] The development of small molecules that disrupt protein-protein interactions is a key goal in addressing a number of disease states. The α-helix is commonly found at protein interaction interfaces and has been the focus of substantial small molecule mimetic efforts. One of the prim...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659501/ https://ncbi.nlm.nih.gov/pubmed/19035840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8022962 |
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