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Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety
A physiological role in satiety is proposed for glucagon-like peptide-1 (GLP-1), secreted by the distal intestine in response to ingested nutrients. Here we report that in rats, ip injection of the GLP-1 receptor (GLP-1-R) antagonist exendin 9-39 (Ex9) elicited hyperphagia, but only at times of day...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Endocrine Society
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659282/ https://ncbi.nlm.nih.gov/pubmed/19074583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1045 |
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