Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086

LP2086 is a family of outer membrane lipoproteins from Neisseria meningitidis, which elicits bactericidal antibodies and are currently undergoing human clinical trials in a bivalent formulation where each antigen represents one of the two known LP2086 subfamilies. Here we report the NMR structure of...

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Detalhes bibliográficos
Main Authors: Mascioni, Alessandro, Bentley, Breagh E., Camarda, Rosaria, Dilts, Deborah A., Fink, Pamela, Gusarova, Viktoria, Hoiseth, Susan K., Jacob, Jaison, Lin, Shuo L., Malakian, Karl, McNeil, Lisa K., Mininni, Terri, Moy, Franklin, Murphy, Ellen, Novikova, Elena, Sigethy, Scott, Wen, Yingxia, Zlotnick, Gary W., Tsao, Désirée H. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659232/
https://ncbi.nlm.nih.gov/pubmed/19103601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808831200
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