Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine

Bivalent rLP2086 (Trumenba), a vaccine for prevention of Neisseria meningitidis serogroup B (NmB) disease, was licensed for use in adolescents and young adults after it was demonstrated that it elicits antibodies that initiate complement-mediated killing of invasive NmB isolates in a serum bacterici...

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Udgivet i:mBio
Main Authors: McNeil, Lisa K., Donald, Robert G. K., Gribenko, Alexey, French, Roger, Lambert, Nathaniel, Harris, Shannon L., Jones, Thomas R., Li, Sheng, Zlotnick, Gary, Vogel, Ulrich, Claus, Heike, Abad, Raquel, Vazquez, Julio A., Borrow, Ray, Findlow, Jamie, Taha, Muhamed-Kheir, Deghmane, Ala-Eddine, Caugant, Dominique A., Kriz, Paula, Musilek, Martin, Wang, Xin, Vuong, Jeni, Mayer, Leonard W., Pride, Michael W., Jansen, Kathrin U., Anderson, Annaliesa S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850321/
https://ncbi.nlm.nih.gov/pubmed/29535195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00036-18
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