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Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

The linker histone H1 generally participates in the establishment of chromatin structure. However, of the seven somatic H1 isotypes in humans some are also implicated in the regulation of local gene expression. Histone H1 isotype 4 (H1.4) represses transcription, and its lysine residue 26 (Lys(26))...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Trojer, Patrick, Zhang, Jin, Yonezawa, Masato, Schmidt, Andreas, Zheng, Haiyan, Jenuwein, Thomas, Reinberg, Danny
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659197/
https://ncbi.nlm.nih.gov/pubmed/19144645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807818200
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