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Leptin Receptor Deficiency is Associated With Upregulation of Cannabinoid 1 Receptors in Limbic Brain Regions

Leptin receptor dysfunction results in overeating and obesity. Leptin regulates hypothalamic signaling that underlies the motivation to hyperphagia, but the interaction between leptin and cannabinoid signaling is poorly understood. We evaluated the role of cannabinoid 1 receptors (CB(1)R) in overeat...

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Main Authors: THANOS, PANAYOTIS K., RAMALHETE, ROBERTO C., MICHAELIDES, MICHAEL, PIYIS, YIANNI K., WANG, GENE-JACK, VOLKOW, NORA D.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659017/
https://ncbi.nlm.nih.gov/pubmed/18563836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20531
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