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A New Approach on Estimation of Solubility and n-octanol/water Partition Coefficient for Organohalogen Compounds

The aqueous solubility (logW) and n-octanol/water partition coefficient (logP(OW)) are important properties for pharmacology, toxicology and medicinal chemistry. Based on an understanding of the dissolution process, the frontier orbital interaction model was suggested in the present paper to describ...

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Bibliografski detalji
Glavni autori: Gao, Shuo, Cao, Chenzhong
Format: Artigo
Jezik:Inglês
Izdano: Molecular Diversity Preservation International (MDPI) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658778/
https://ncbi.nlm.nih.gov/pubmed/19325840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms9060962
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