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Empirical prediction of peptide octanol-water partition coefficients

Peptides are of great therapeutic potential as vaccines and drugs. Knowledge of physicochemical descriptors, including the partition coefficient P (commonly expressed in logarithm form: logP), is useful for screening out unsuitable molecules and also for the development of predictive Quantitative St...

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Auteurs principaux: Hattotuwagama, Channa K, Flower, Darren R
Format: Artigo
Langue:Inglês
Publié: Biomedical Informatics Publishing Group 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891700/
https://ncbi.nlm.nih.gov/pubmed/17597903
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