Dyslipidemia and Atherosclerosis Induced by Chronic Intermittent Hypoxia Are Attenuated by Deficiency of Stearoyl Coenzyme A Desaturase

Obstructive sleep apnea leads to chronic intermittent hypoxia (CIH) and is associated with atherosclerosis. We have previously shown that C57BL/6J mice exposed to CIH and a high-cholesterol diet develop dyslipidemia, atherosclerosis of the aorta, and upregulation of a hepatic enzyme of lipoprotein s...

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Autori principali: Savransky, Vladimir, Jun, Jonathan, Li, Jianguo, Nanayakkara, Ashika, Fonti, Shannon, Moser, Ann B., Steele, Kimberly E., Schweitzer, Michael A., Patil, Susheel P., Bhanot, Sanjay, Schwartz, Alan R., Polotsky, Vsevolod Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658638/
https://ncbi.nlm.nih.gov/pubmed/18832746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.178533
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